Quantum-Enhanced BioMEMS for Ultra-Sensitive Detection of Pathogens in Clinical Diagnostics

Defne Duman

doi:10.62802/58mgxe11

Authors

Defne Duman Robert College Author https://orcid.org/0009-0008-6932-9871

DOI:

https://doi.org/10.62802/58mgxe11

Keywords:

quantum sensing, BioMEMS, pathogen detection, nanomaterials, quantum tunneling, biophotonics, microfluidics, sustainable healthcare innovation

Abstract

Rapid and accurate detection of pathogens at very low concentrations is crucial for protecting public health, especially during outbreaks. In this project, I explore how ideas from quantum physics can be combined with biological microelectromechanical systems (BioMEMS) to build more sensitive diagnostic devices. The main goal is to help these chips pick up extremely weak signals from viruses or bacteria while reducing noise and false readings.

The work focuses on three approaches: quantum tunneling, spin-based readout (such as nitrogen-vacancy centers in diamond), and quantum-enhanced biophotonic techniques. Using simple computational simulations and conceptual models, I examine how these methods could lower detection limits in microfluidic chips and make the data more reliable. A focused review of recent research on BioMEMS, nanomaterials, and quantum biophotonics is also carried out to understand current challenges and realistic design options.

Overall, the project suggests that quantum-enhanced BioMEMS could help create smaller, faster, and more affordable diagnostic tools. Such devices support the United Nations Sustainable Development Goals for better health (SDG 3) and innovation in industry and infrastructure (SDG 9) by making advanced healthcare technology more accessible around the world.

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